Background: Diabetic foot is a serious complication of diabetes mellitus and a leading cause of lower-limb amputation. This study aimed to determine the incidence of diabetic foot amputation and describe the demographic and clinical characteristics of diabetic patients in Jalalabad City, Afghanistan.

Methods: A descriptive cross-sectional study was conducted among 87 diabetic patients with diabetic foot complications in Jalalabad City during 2025. Data were collected using a structured questionnaire and analyzed using Microsoft Excel. Descriptive statistics (frequencies and percentages) were used to summarize the findings.

Results: Most participants were male (73.56%), aged 50 years or older (78.16%), lived in rural areas (73.56%), had no formal education (67.82%), and had Type 2 diabetes mellitus (97.70%). Foot ulcers (95.40%), infection (85.06%), gangrene (80.46%), and toe amputation (89.66%) were highly prevalent. Overall, 64.37% had undergone foot or leg amputation, with most amputations occurring in 2025 (77.01%). Delayed hospital visits (89.66%), limited foot care education (51.72%), poor awareness of HbA1c (67.82%), and a high prevalence of hypertension (94.25%) and kidney disease (85.06%) were also observed.

Conclusion: Diabetic foot amputation was common among diabetic patients in Jalalabad City and was associated with delayed healthcare seeking, inadequate foot care knowledge, poor diabetes awareness, and multiple comorbidities. Strengthening diabetes education, promoting regular foot care, and improving access to early diagnosis and treatment may help reduce diabetes-related amputations.

Keywords: Diabetic foot, Amputation, Diabetes mellitus, Foot ulcer, Gangrene.